| 2021-22 United Soccer Coaches Winter Boys High School All-Region | ||||
| Pos. | Player | Class | School | City, State |
| K | Elijah Betancourt | So. | Jordan High School | Fulshear, Texas |
| K | Jasper Broad | Sr. | Ransom Everglades School | Miami, Fla. |
| D | Colin Bailey | Sr. | Wiregrass Ranch High School | Wesley Chapel, Fla. |
| D | Ben Bucic | Jr. | Jordan High School | Fulshear, Texas |
| D | Ty Koc | Sr. | Seven Lakes High School | Katy, Texas |
| D | Tomas Olivares | Sr. | Harlan High School | San Antonio, Texas |
| D | Javier Ortega | Sr. | Dripping Springs High School | Dripping Springs, Texas |
| M | Erik Alvarado | Sr. | Central Catholic High School | San Antonio, Texas |
| M | Santiago Castaneda | Jr. | Tampa Preparatory School | Tampa, Fla. |
| M | Kassen Dilworth | Jr. | Samuel Clemens High School | Schertz, Texas |
| M | Kohyn Gough | Sr. | Celina High School | Celina, Texas |
| M | Joel Hernandez | Sr. | Lone Star High School | Frisco, Texas |
| M | Adam Knutson | Sr. | Dripping Springs High School | Dripping Springs, Texas |
| M | Aidan Morrison | So. | Seven Lakes High School | Katy, Texas |
| M | Clay Murador | Jr. | Aledo High School | Aledo, Texas |
| M | Samuel Schoensee | Sr. | The Canterbury School | Fort Myers, Fla. |
| M | Walker Stone | Sr. | Coppell High School | Coppell, Texas |
| M | Jason Sukow | Sr. | Ronald Reagan High School | San Antonio, Texas |
| M | Cristian Torres | Sr. | John Paul II High School | Plano, Texas |
| F | Chandler Crawshaw | Sr. | Mulberry High School | Mulberry, Fla. |
| F | Christian Fairchild | Sr. | Jesuit High School | Tampa, Fla. |
| F | Leonel Gutierrez | So. | Salpointe Catholic High School | Tucson, Ariz. |
| F | Asher Jones | So. | Tampa Preparatory School | Temple Terrace, Fla. |
| F | Kortay Koc | Fr. | Seven Lakes High School | Katy, Texas |
| F | Braden Masker | Sr. | Arnold High School | Panama City Beach, Fla. |
| F | Omar Mora | Sr. | Eastlake High School | El Paso, Texas |
| F | Logan Murphy | Jr. | John Paul II High School | Plano, Texas |
| F | Noa Stasic | So. | Seven Lakes High School | Katy, Texas |
| F | Jace Windom | Sr. | Lutheran South Academy | Houston, Texas |
